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. 2017 May 3;8(42):71699–71708. doi: 10.18632/oncotarget.17599

Table 2. Surgery and other therapy information of NENs from different anatomic sites.

Treatment method Total distribution (N=2010) Gastric cardiac NENs (N=234) Gastric body NENs (N=309) Rectal NENs (N=595) Pancreatic NENs (N=633) Other NENs (N=239) P value
n (%) n (%) n (%) n (%) n (%) n (%)
Surgery type 1820 (100.0) 225 (100.0) 265 (100.0) 533 (100.0) 585 (100.0) 212 (100.0)
 Radical surgery 1699 (93.4) 221 (98.2) 246 (92.8) 481 (90.2) 562 (96.1) 189 (89.2) 0.000*
 Palliative surgery 121 (6.6) 4 (1.8) 19 (7.2) 52 (9.8) 23 (3.9) 23 (10.8)
Surgery method 1699 (100.0) 204 (100.0) 265 (100.0) 464 (100.0) 555 (100.0) 211 (100.0)
 Open surgery 1446 (85.1) 199 (97.5) 241 (90.9) 309 (66.6) 507 (91.4) 190 (90.0) 0.000*
 Laparoscopic surgery 107 (6.3) 5 (2.5) 19 (7.2) 23 (5.0) 47 (8.5) 13 (6.2)
 Endoscopic surgery 146 (8.6) 0 (0) 5 (1.9) 132 (28.4) 1 (0.2) 8 (3.8)
Chemotherapy 1967 (100.0) 224 (100.0) 304 (100.0) 579 (100.0) 627 (100.0) 233 (100.0)
 Yes 393 (20.0) 82 (36.6) 115 (37.8) 72 (12.4) 69 (11.0) 55 (23.6) 0.000*
 No 1574 (80.0) 142 (63.4) 189 (62.2) 507 (87.6) 558 (89.0) 178 (76.4)
Biotherapy 1982 (100.0) 231 (100.0) 307 (100.0) 589 (100.0) 621 (100.0) 234 (100.0)
 Yes 195 (9.8) 0 (0) 6 (2.0) 3 (0.5) 171 (27.5) 15 (6.4) 0.000*
 No 1787 (90.2) 231 (100.0) 301 (98.0) 586 (99.5) 450 (72.5) 219 (93.6)
Target therapy 1980 (100.0) 226 (100.0) 305 (100.0) 585 (100.0) 629 (100.0) 235 (100.0)
 Yes 14 (0.7) 0 (0) 6 (2.0) 0 (0) 6 (1.0) 2 (0.9) 0.004*
 No 1966 (99.3) 226 (100.0) 299 (98.0) 585 (100.0) 623 (99.0) 233 (99.1)
Radiotherapy 1997 (100.0) 231 (100.0) 308 (100.0) 590 (100.0) 632 (100.0) 236 (100.0)
 Yes 43 (2.2) 7 (3.0) 5 (1.6) 20 (3.4) 5 (0.8) 6 (2.5) 0.024*
 No 1954 (97.8) 224 (97.0) 303 (98.4) 570 (96.6) 627 (99.2) 230 (97.5)

* Significantly different, using Mantel-Haenszel χ2 test or Fisher's exact tests.