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. 2017 May 13;8(42):71709–71724. doi: 10.18632/oncotarget.17845

Table 1. Metabolic stability of the peptides.

Human Liver Microsomes Mouse Liver Microsomes
Peptide T1/2 (min) % Remaining at 20 min % Remaining at 60 min T1/2 (min) % Remaining at 20 min % Remaining at 60 min
P60 N.D. N.D. N.D. N.D. N.D. N.D.
P60-2A < 2.5 0 0 < 2.5 0 0
CM-1215 5.30 6.20 0 8 12 0
CM-1315 61.7 48.7 46.1 63.8 62.7 47.7