Table 3. Top 10 down- or upregulated DEGs between LADC and LSCC in lung cancer dataset, GSE43580.

Probe set ID	Gene symbol	Gene description	Gene feature	Fold change
209125_at	KRT6A	keratin 6A	downregulation	−53.2466
235075_at	DSG3	desmoglein 3	downregulation	−45.44
206165_s_at	CLCA2	chloride channel accessory 2	downregulation	−38.0985
209863_s_at	TP63	tumor protein p63	downregulation	−28.6096
213796_at	SPRR1A	small proline-rich protein 1A	downregulation	−27.828
201820_at	KRT5	keratin 5	downregulation	−26.5195
206032_at	DSC3	desmocollin 3	downregulation	−25.687
213680_at	KRT6B	keratin 6B	downregulation	−25.5837
217272_s_at	SERPINB13	serpin peptidase inhibitor, clade B (ovalbumin), member 13	downregulation	−22.7939
209351_at	KRT14	keratin 14	downregulation	−21.4751
216623_x_at	TOX3	TOX high mobility group box family member 3	upregulation	12.48837
228979_at	SFTA3	surfactant associated 3	upregulation	9.698342
244056_at	SFTA2	surfactant associated 2	upregulation	9.34222
220393_at	LGSN	lengsin, lens protein with glutamine synthetase domain	upregulation	7.272057
223806_s_at	NAPSA	napsin A aspartic peptidase	upregulation	6.387242
211024_s_at	NKX2-1	NK2 homeobox 1	upregulation	6.235382
240304_s_at	TMC5	transmembrane channel-like 5	upregulation	5.886752
229030_at	CAPN8	calpain 8	upregulation	5.558286
209016_s_at	KRT7	keratin 7	upregulation	5.197863
206239_s_at	SPINK1	serine peptidase inhibitor, Kazal type 1	upregulation	5.028636