Figure 5. The impact of compound WX-132-18B on cell cycle of A549 cells.

A549 cells were treated with vehicle (0.1% dimethyl sulfoxide), colchicine (300 nM), vincristine (300 nM), taxol (100 nM), or WX-132-18B (3 nM) for 24 h and then assayed via flow cytometry. The bar chart shows the percentage of cell cycle distribution based on flow cytometry results. Values are mean±SD, n=3. *P<0.05, **P<0.01, ***P<0.001, compared with control group.