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. 2017 May 9;8(42):71782–71796. doi: 10.18632/oncotarget.17710

Figure 8. WX-132-18B inhibited tumor growth in vivo.

Figure 8

(A) Effects of tumor growth inhibition of WX-132-18B in S180 xenograft KM mice, H460 xenograft and BGC-823 xenograft Nu/Nu nude mice. Mice were treated with taxol or different doses (0.25, 0.5 and 1.0 mg/kg) of WX-132-18B for three weeks. Tumor volumes were measured before treatment and at the indicated days of treatment. At the end of the experiment, tumors were resected and weighed. Values are means±SD of tumor volume or weight for all the tested mice in each group. (B) Histological examination and immunohistochemical analysis of the expression and distribution of CD31, caspase 3, and Ki67 in BGC-823 xenograft tumor. The red arrow indicates blood vessels. Scale bar, 100 μm.