Table 3. EC50 values of testing compounds on tubulin parameters in A549 cells.
EC50 (nM) | |||
---|---|---|---|
Intensity*Area | Elongation | 1/(Form Factor) | |
Taxol | 75.84±6.73 | - | 30.89 |
Colchicine | 105.5 | 111.62 | 114.1 |
Vincristine | 293.2 | 352.03±18.10 | 30.89 |
WX-132-18B | 9.43 | 3.12 | 2.99 |
Cells were treated with different compounds for 24 h. Values are mean±SD, n=3