Table 1. Correlation between Barx1, MMP9 and MGAT5 expression and clinicopathological characteristics in 315 HCC tissues.
Tumor Barx1 expression | Tumor MMP9 expression | Tumor MGAT5 expression | ||||||||
---|---|---|---|---|---|---|---|---|---|---|
Low | High | P Value | Low | High | P Value | Low | High | P Value | ||
(n=198) | (n=117) | (n=133) | (n=182) | (n=119) | (n=196) | |||||
Age(year) | <60 | 128 | 80 | 0.499 | 93 | 115 | 0.212 | 85 | 123 | 0.115 |
≥60 | 70 | 37 | 40 | 67 | 34 | 73 | ||||
Sex | Female | 29 | 23 | 0.247 | 27 | 25 | 0.121 | 25 | 27 | 0.094 |
Male | 169 | 94 | 106 | 157 | 94 | 169 | ||||
Serum AFP(ng/ml) | <20 | 52 | 33 | 0.707 | 40 | 45 | 0.291 | 37 | 48 | 0.201 |
≥20 | 146 | 84 | 93 | 137 | 82 | 148 | ||||
HBV | Yes | 173 | 101 | 0.789 | 118 | 156 | 0.433 | 107 | 167 | 0.228 |
No | 25 | 16 | 15 | 26 | 12 | 29 | ||||
Cirrhosis | Present | 168 | 104 | 0.313 | 113 | 159 | 0.54 | 100 | 172 | 0.351 |
Absent | 30 | 13 | 20 | 23 | 19 | 24 | ||||
Tumor No. | Single | 172 | 98 | 0.023* | 103 | 157 | 0.256 | 91 | 169 | 0.027* |
Multiple | 26 | 29 | 30 | 25 | 28 | 27 | ||||
Tumor Size(cm) | <5 | 59 | 53 | 0.005* | 58 | 54 | 0.011* | 59 | 53 | 0.000* |
≥5 | 139 | 64 | 75 | 128 | 60 | 143 | ||||
Tumor differentiation | I-II | 139 | 102 | 0.001* | 90 | 151 | 0.002* | 103 | 138 | 0.001* |
III-IV | 59 | 15 | 43 | 31 | 16 | 58 | ||||
TNM stage | I-II | 61 | 59 | 0.001* | 41 | 79 | 0.023* | 58 | 62 | 0.002* |
III | 137 | 58 | 92 | 103 | 61 | 134 |
Abbreviation: AFP, αlpha-fetoprotein; HBV, hepatitis B virus
*P<0.05.