Table 4. Diagnostic performance of GMS staining, BAL fluid PCR, sputum PCR, serum PCR, and the combinations of sputum PCR and serum PCR for PCP diagnosis.
| Test | Sen (%) 95% CI | Spe (%) 95% CI | PPV (%) | NPV (%) |
|---|---|---|---|---|
| GMS staining | 51.4 (34.0–68.6) | 100 (90.3–100) | 100 | 67.9 |
| BAL fluid PCR | 97.1 (85.1–99.9) | 86.1 (70.5–95.3) | 87.2 | 96.9 |
| Sputum PCR | 91.4 (76.9–98.2) | 86.1 (70.5–95.3) | 86.5 | 91.2 |
| Serum PCR | 68.6 (50.7–83.1) | 97.2 (85.5–99.9) | 96.0 | 76.1 |
| Sputum PCR | ||||
| AND serum PCR | 62.9 (44.9–78.5) | 100 (90.3–100) | 100 | 73.5 |
| Sputum PCR | ||||
| OR serum PCR | 97.1 (85.1–99.9) | 83.3 (67.2–93.6) | 85.0 | 96.8 |