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. 2017 May 20;8(42):71946–71953. doi: 10.18632/oncotarget.18037

Table 5. Study summary of serum DNA in PCP diagnosis.

Year PCR method PCR target Sensitivity (%) Specificity (%) Reference
1992 C-PCR DHFR 12/14 (85.7) 6/6 (100) [13]
2012 qPCR mt LSU rRNA 9/10 (90.0) 60/60 (100) [14]
1998 N-PCR ITSs 10/14 (71.4) 26/26 (100) [15]
1996 N-PCR mt LSU rRNA 0/15 (0) - [16]
1996 C-PCR 5S rRNA 10/10 (100) - [17]
1995 N-PCR ITSs 27/27 (100) 18/18 (100) [18]
DHFR 2/20 (10.0) 18/18 (100)
1997 C-PCR mt LSU rRNA 1/13 (7.7) 19/22 (86.4) [19]
1991 C-PCR DHFR 7/18 (38.9) - [20]

Abbreviations: C-PCR, conventional PCR; N-PCR, nested PCR; DHFR, dihydrofolate reductase; ITSs, internal transcribed spacers.