Table 3. Development of cloned embryos derived from the abnormal imprinting donor cells with H19 knockdown.
Group | No. embryos (Rep.) | No. embryos cleaved (% ± SEM) | No. blastocysts (% ± SEM) |
---|---|---|---|
siRNA-control | 171 (5) | 135 (78.82 ± 1.91)a | 22 (12.85 ± 1.37)a |
siRNA-negative | 184 (5) | 146 (79.32 ± 1.73)a | 21 (11.34 ± 1.28)a |
siRNA-positive | 173 (5) | 151 (87.28 ± 1.85)b | 48 (27.90 ± 1.84)b |
a–bValues in the same column with different superscripts differ significantly (P < 0.05).