Table 1. IC50 value and RIs of HepG2 and HepG2/5-FU cells treated with different chemotherapeutic agents.
Drugs | HepG2 IC50(μmol/L) | HepG2/5-FU | |
---|---|---|---|
IC50(μmol/L) | RI | ||
5-fluorouracil | 44.5±1.0 | 400.4±8.3** | 9.3±1.5 |
Cisplatin | 3.5±0.2 | 100.9±6.2** | 36.3±4.2 |
Oxaliplatin | 9.8±1.2 | 89.3±5.1** | 10.1±1.9 |
IC50 values and RI were determined by the CCK-8 method. Data are expressed as means ± SD. **P < 0.01 versus the parental cells.