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. 2017 Aug 10;8(42):72652–72665. doi: 10.18632/oncotarget.20194

Table 1. IC50 value and RIs of HepG2 and HepG2/5-FU cells treated with different chemotherapeutic agents.

Drugs HepG2 IC50(μmol/L) HepG2/5-FU
IC50(μmol/L) RI
5-fluorouracil 44.5±1.0 400.4±8.3** 9.3±1.5
Cisplatin 3.5±0.2 100.9±6.2** 36.3±4.2
Oxaliplatin 9.8±1.2 89.3±5.1** 10.1±1.9

IC50 values and RI were determined by the CCK-8 method. Data are expressed as means ± SD. **P < 0.01 versus the parental cells.

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