Table 2. IC50 values and RIs of Bel7402 and Bel7402/5-FU cells treated with different chemotherapeutic agents.
Drugs | Bel7402 IC50(μmol/L) | Bel7402/5-FU | |
---|---|---|---|
IC50(μmol/L) | RI | ||
5-fluorouracil | 38.3±0.7 | 455.2±3.1** | 11.7±0.3 |
Cisplatin | 3.9±0.8 | 102.1±5.2** | 31.5±7.0 |
Oxaliplatin | 8.9±0.4 | 118.5±2.2** | 14.3±0.8 |
IC50 values and RI were determined by the CCK-8 method. Data are expressed as means ± SD. **P < 0.01 versus the parental cells.