Skip to main content
. 2017 Aug 10;8(42):72652–72665. doi: 10.18632/oncotarget.20194

Table 4. IC50 values and RIs of Bel7402/5-FU cells treated with different chemotherapeutic agents in the presence or absence of Ubenimex for 24 h.

Drugs Bel7402 IC50(μmol/L) Bel7402 /5-FU Bel7402 /5-FU + Ubenimex
IC50(μmol/L) RI IC50(μmol/L) RI
5-fluorouracil 39.2±1.2 456.2±4.1 11.4±0.4 186.2±2.5** 3.9±0.2**
Cisplatin 4.0±0.9 100.9±6.2 30.5±7.2 52.3±1.9** 11±2.9**
Oxaliplatin 8.5±0.3 120.3±3.2 14.1±0.3 60.5±1.1** 7.0±0.4**

IC50 values and RI were determined by the CCK-8 method. Data are expressed as means ±SD. **P<0.01 versus Cisplatin; 5-fluorouracil and Oxaliplatin without Ubenimex.

HHS Vulnerability Disclosure