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. 2017 Aug 18;8(42):72773–72787. doi: 10.18632/oncotarget.20347

Figure 3. H3R117 mono-ADP-ribosylation affects the proliferation of colon carcinoma.

Figure 3

(A) The proliferation inhibitory rate of mutant groups increased(*p<0.05). (B&C) The soft agar cloning method showed that the mutant groups formed fewer cell clones, compared with the control groups(***p<0.001). (D&E) FCM showed that the proliferation index(PI) of the mutant groups were lower than for the control groups(*p<0.05). (F&G) The weight and volume of mutant LOVO cells transplanted tumors in nude mice showed a significant reduction, compared with the control groups(**p<0.01).