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. 2017 Jun 16;8(42):72939–72949. doi: 10.18632/oncotarget.18513

Table 1. Characteristics of all included studies in this meta-analysis.

Study Country Publication Genotyping method Number of patient Treatment toxicities Median follow-up specimen
Sweeney, et al. [17] America 2000 PCR-RFLP 240 chemotherapy + radiotherapy, chemotherapy, radiotherapy NP 58 months tissue
Yang, et al. [29] China 2005 Multiplex PCR 1034 chemotherapy NP 5.3 years blood
Ambrosone, et al. [16] German 2006 Multiplex PCR 446 radiotherapy after surgery skin toxicities NP blood
Zárate, et al. [39] Spain 2007 PCR-RFLP 94 chemotherapy haematological and non-haematological NP blood
Syamala, et al. [14] India 2008 PCR 347 NP NP NP blood
Kuptsova, et al. [18] German 2008 Multiplex PCR 390 radiotherapy after surgery telangiectasia 4.1 years blood
Bewick, et al. [19] Canada 2008 PCR 95 chemotherapy NP 10.4 months blood or bone marrow
Tang, et al. [20] China 2009 PCR 126 chemotherapy NP 6 weeks blood
Oliveira, et al. [21] Brazil 2010 PCR-RFLP 40 chemotherapy NP NP blood
Yao, et al. [40] America 2010 PCR-RFLP 458 chemotherapy hematologic 10.8 years tumor cell
Zhong, et al. [22] China 2010 PCR 132 chemotherapy NP 9 weeks blood
Zhang (1), et al. [37] China 2011 PCR-RFLP 120 chemotherapy hematologic NP blood
Bai, et al. [23] China 2012 PCR-RFLP 159 chemotherapy NP 4 years blood
Terrazzino, et al. [24] Italy 2012 PCR 237 radiotherapy skin fibrosis 63 days blood
Raabe, et al. [25] German 2012 PCR-RFLP 83 radiotherapy erythema NP blood
Ji, et al. [26] China 2012 PCR 153 chemotherapy neutropenia 51 months blood
Tulsyan, et al. [27] India 2013 PCR-RFLP 100 chemotherapy hematologic NP blood
Duggan, et al. [28] America 2013 PCR 533 surgery, surgery and radiotherapy, and chemotherapy NP 11.29 years blood
Zhang (2), et al. [38] China 2013 PCR-CTPP 219 chemotherapy NP 4 years blood
Zhao, et al. [15] China 2014 PCR 252 chemotherapy hematologic NP blood
Sugishita, et al. [30] Japan 2014 PCR 102 chemotherapy hematologic 967 days blood
Liu, et al. [34] China 2014 PCR 382 chemotherapy after surgery NP NP blood
Zhou, et al. [31] China 2015 PCR 420 chemotherapy after surgery NP 5 years blood
Wang (1), et al. [32] China 2015 PCR-RFLP 310 chemotherapy NP 5 years blood
Wang (2), et al. [33] China 2015 PCR-RFLP 262 chemotherapy NP NP blood
Islam, et al. [35] Bangladesh 2015 PCR-RFLP 256 chemotherapy hematologic NP blood
Eckhoff, et al. [36] Denmark 2015 PCR 150 chemotherapy docetaxel-induced peripheral neuropathy 7.5 months blood
Yuan, et al. [41] China 2015 PCR-RFLP 273 chemotherapy NP 5 years blood

PCR polymerase chain reaction, NP not provided