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. 2017 Apr 14;8(42):73133–73143. doi: 10.18632/oncotarget.17111

Table 1. Clinical and biochemical characteristics of the study patients.

Characteristics Total (n=169) Underweight or Normal-weight (BMI<24, n=57) Overweight or Obesity (BMI≥24, n=112) P-Value
Age (years) 51.33±9.83 51.86±9.53 51.06±10.02 0.620
Male, n (%) 110(65.01%) 33(57.89%) 77(68.75%) 0.162
Current smokers (n (%)) 61(36.09%) 16(28.07%) 45(40.18%) 0.121
Current alcohol (n (%)) 32(18.93%) 9(15.80%) 23(20.54%) 0.457
Hypertension (n (%)) 68(40.24%) 15(26.32%) 53(47.32%) 0.008
Family history of T2DM (n (%)) 63(37.28%) 18(31.58%) 45(40.18%) 0.274
BMI (kg/m2) 25.36±3.09 22.28±1.46 26.93±2.46 <0.001
WC (cm) 87.54±7.56 81.96±5.27 90.38±6.96 <0.001
ALT (u/L)* 25.00 (16.00, 40.50) 19.00 (13.00, 33.00) 26.50 (19.25, 44.75) 0.003
AST (u/L)* 20.00 (15.00, 28.00) 18.00 (14.00, 25.00) 20.00 (15.00, 30.00) 0.080
TC (mmol/l) 5.32±1.00 5.14±1.00 5.42±1.00 0.081
TG (mmol/l)* 1.91 (1.25, 2.68) 1.68(1.18, 2.55) 1.98 (1.29, 2.99) 0.057
HDL-C (mmol/l)* 1.20 (1.01, 1.53) 1.34(1.03, 1.64) 1.17 (1.01, 1.50) 0.290
LDL-C (mmol/l) 2.77±0.62 2.64±0.68 2.83±0.58 0.048
UA (umol/l) 306.83±94.06 273.56±75.85 323.94±98.34 0.008
Creatinine (umol/l) 65.36±15.54 63.34±15.62 66.34±15.48 0.248

Abbreviations: BMI, body mass index; WC, waist circumference; ALT, alanine aminotransferase; AST, aspertate aminotransferase; TC, total cholesterol; TG, triglyceride; HDL-C, high-density lipoprotein cholesterol; LDL-C, low-density lipoprotein cholesterol; UA, uric acid.

* ALT, AST, TG and HDL were log10-transformed because of non-normal distribution.