Table 1. Clinical and biochemical characteristics of the study patients.
Characteristics | Total (n=169) | Underweight or Normal-weight (BMI<24, n=57) | Overweight or Obesity (BMI≥24, n=112) | P-Value |
---|---|---|---|---|
Age (years) | 51.33±9.83 | 51.86±9.53 | 51.06±10.02 | 0.620 |
Male, n (%) | 110(65.01%) | 33(57.89%) | 77(68.75%) | 0.162 |
Current smokers (n (%)) | 61(36.09%) | 16(28.07%) | 45(40.18%) | 0.121 |
Current alcohol (n (%)) | 32(18.93%) | 9(15.80%) | 23(20.54%) | 0.457 |
Hypertension (n (%)) | 68(40.24%) | 15(26.32%) | 53(47.32%) | 0.008 |
Family history of T2DM (n (%)) | 63(37.28%) | 18(31.58%) | 45(40.18%) | 0.274 |
BMI (kg/m2) | 25.36±3.09 | 22.28±1.46 | 26.93±2.46 | <0.001 |
WC (cm) | 87.54±7.56 | 81.96±5.27 | 90.38±6.96 | <0.001 |
ALT (u/L)* | 25.00 (16.00, 40.50) | 19.00 (13.00, 33.00) | 26.50 (19.25, 44.75) | 0.003 |
AST (u/L)* | 20.00 (15.00, 28.00) | 18.00 (14.00, 25.00) | 20.00 (15.00, 30.00) | 0.080 |
TC (mmol/l) | 5.32±1.00 | 5.14±1.00 | 5.42±1.00 | 0.081 |
TG (mmol/l)* | 1.91 (1.25, 2.68) | 1.68(1.18, 2.55) | 1.98 (1.29, 2.99) | 0.057 |
HDL-C (mmol/l)* | 1.20 (1.01, 1.53) | 1.34(1.03, 1.64) | 1.17 (1.01, 1.50) | 0.290 |
LDL-C (mmol/l) | 2.77±0.62 | 2.64±0.68 | 2.83±0.58 | 0.048 |
UA (umol/l) | 306.83±94.06 | 273.56±75.85 | 323.94±98.34 | 0.008 |
Creatinine (umol/l) | 65.36±15.54 | 63.34±15.62 | 66.34±15.48 | 0.248 |
Abbreviations: BMI, body mass index; WC, waist circumference; ALT, alanine aminotransferase; AST, aspertate aminotransferase; TC, total cholesterol; TG, triglyceride; HDL-C, high-density lipoprotein cholesterol; LDL-C, low-density lipoprotein cholesterol; UA, uric acid.
* ALT, AST, TG and HDL were log10-transformed because of non-normal distribution.