Table 3. Univariate analysis for DFS and OS for all NSCLC patients.
| Variables | P value | DFS HR (95 % CI) | P value | OS HR (95 % CI) | |
|---|---|---|---|---|---|
| Age (≤60/>60) | 0.633 | 0.963(0.825-1.125) | 0.458 | 0.943(0.808-1.101) | |
| Sex (female/male) | 0.703 | 0.969(0.822-1.141) | 0.286 | 0.915(0.777-1.077) | |
| Smoking status (yes/no) | 0.432 | 1.068(0.905-1.259) | 0.110 | 1.144(0.970-1.350) | |
| Tumor location (left/right) | 0.909 | 1.009(0.862-1.182) | 0.947 | 1.005(0.858-1.178) | |
| Lesion type (central/peripheral) | 0.006 | 1.264(1.070-1.492) | 0.004 | 1.276(1.081-1.507) | |
| Resection type (pneumonectomy/lobectomy) | 0.034 | 1.275(1.019-1.597) | 0.035 | 1.274(1.017-1.595) | |
| Histological subtype (SqCC/non-SqCC) | 0.870 | 1.013(0.868-1.183) | 0.894 | 0.990(0.848-1.155) | |
| Pathological stage (IIIA/I, II) | <0.001 | 2.507(2.145-2.930) | <0.001 | 2.484(2.126-2.903) | |
| LDH (≥174.0/<174.0 UL−1) | 0.036 | 1.180(1.015-1.377) | 0.049 | 1.168(1.001-1.364) | |
| ALP (≥71.0/<71.0 UL−1) | 0.008 | 1.233(1.056-1.439) | 0.005 | 1.246(1.067-1.455) | |
| Hb (≥130.5/<130.5 gL−1) | <0.001 | 0.662(0.560-0.783) | <0.001 | 0.677(0.572-0.801) | |
| Albumin (≥44.9/<44.9 gL−1) | <0.001 | 0.682(0.574-0.810) | <0.001 | 0.691(0.582-0.822) | |
| WBC count (≥7.8/<7.8× 103 mm-3) | <0.001 | 1.343(1.139-1.583) | 0.001 | 1.328(1.127-1.565) | |
| PLT (≥300/<300 ×109L−1) | <0.001 | 1.435(1.206-1.706) | <0.001 | 1.437(1.208-1.706) | |
| D-dimer (≥0.1/<0.1 mgL−1) | <0.001 | 1.442(1.235-1.684) | <0.001 | 1.359(1.163-1.588) | |
| Fibrinogen (≥3.6/<3.6 gL−1) | <0.001 | 1.405(1.203-1.641) | <0.001 | 1.451(1.242-1.695) | |
| LMR (≥3.6/<3.6) | <0.001 | 0.537(0.460-0.627) | <0.001 | 0.532(0.456-0.621) | |
| COP-LMR (1, 2/0) | <0.001 | 1.915(1.646-2.230) | <0.001 | 1.909(1.641-2.223) | |
Abbreviations: DFS, disease-free survival; OS, overall survival; HR, hazard ratio; CI, confidence interval; NSCLC, non-small cell lung cancer, SqCC, squamous cell carcinoma; LDH, lactate dehydrogenase; ALP, alkaline phosphatase; Hb, hemoglobin; WBC, white blood cell; PLT, platelet count; LMR, lymphocyte to monocyte ratio; COP-LMR, combination of preoperative platelet count and lymphocyte to monocyte ratio. HR was calculated with reference to the last category. P value <0.05 is statistically significant.