Table 4. Multivariate analysis for DFS and OS for all NSCLC patients.
| Variables | P value | DFS HR (95 % CI) | P value | OS HR (95 % CI) | |
|---|---|---|---|---|---|
| Lesion (central/peripheral) | 0.255 | 1.116(0.924-1.347) | 0.319 | 1.102(0.911-1.333) | |
| Resection type (pneumonectomy/lobectomy) | 0.703 | 1.050(0.818-1.348) | 0.870 | 1.021(0.793-1.314) | |
| Pathological stage (IIIA/I, II) | <0.001 | 2.395(2.045-2.807) | <0.001 | 2.416(2.063-2.829) | |
| LDH (≥174.0/ <174.0 UL−1) | 0.056 | 1.199(0.995-1.407) | 0.066 | 1.161(0.990-1.361) | |
| ALP (≥71.0/<71.0 UL−1) | 0.378 | 1.077(0.914-1.268) | 0.238 | 1.104(0.937-1.301) | |
| Hb (≥130.5/<130.5 gL−1) | 0.001 | 0.745(0.623-0.890) | 0.001 | 0.743(0.621-0.889) | |
| Albumin (≥44.9/<44.9 gL−1) | 0.065 | 0.828(0.698-1.014) | 0.074 | 0.844(0.701-1.016) | |
| WBC count (≥7.8/<7.8× 103 mm-3) | 0.069 | 1.199(0.995-1.426) | 0.110 | 1.152(0.968-1.372) | |
| D-dimer (≥0.1/<0.1 mgL−1) | 0.014 | 1.223(1.041-1.436) | 0.047 | 1.177(1.002-1.382) | |
| Fibrinogen (≥3.6/<3.6 gL−1) | 0.792 | 1.024(0.859-1.221) | 0.402 | 1.079(0.904-1.287) | |
| LMR (≥3.6/<3.6) | 0.464 | 0.873(0.607-1.256) | 0.245 | 0.806(0.561-1.159) | |
| PLT (≥300/<300 ×109L−1) | 0.100 | 1.168(0.969-1.400) | 0.125 | 1.150(0.960-1.393) | |
| COP-LMR (1, 2/0) | <0.001 | 1.789(1.311-2.445) | <0.001 | 1.919(1.404-2.618) | |
Abbreviations: DFS, disease-free survival; OS, overall survival; NSCLC, non-small cell lung cancer; HR, hazard ratio; CI, confidence interval; LDH, lactate dehydrogenase; ALP, alkaline phosphatase; Hb, hemoglobin; WBC, white blood cell; COP-LMR, combination of preoperative platelet count and lymphocyte to monocyte ratio. HR was calculated with reference to the last category. P value <0.05 is statistically significant.