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. Author manuscript; available in PMC: 2018 Nov 1.
Published in final edited form as: Acta Physiol (Oxf). 2017 Jun 27;221(3):204–220. doi: 10.1111/apha.12899

Figure 2. TLR4 blockade with LPS-RS preserves autoregulatory behaviour.

Figure 2

Co-treatment with the TLR4 antagonist, LPS-RS, preserves afferent arteriole autoregulatory behaviour in LPS treated kidneys. (a): Effect of renal perfusion pressure changes on afferent arteriole diameter in kidneys from control (black diamonds), LPS (1 mg kg−1; i.p.; grey squares), and LPS + LPS-RS (5 mg; i.p.; blue triangles) treated groups. (b): Data are expressed as a percent of the baseline diameter at 100 mmHg. Each data point represents the mean ± SE. n=6 per group. * P<0.05 vs. baseline diameter in the same group. Ϯ P<0.05 vs. control group for the same perfusion pressure. # P<0.05 vs. LPS-RS for the same perfusion pressure.