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. Author manuscript; available in PMC: 2018 Nov 1.
Published in final edited form as: Acta Physiol (Oxf). 2017 Jun 27;221(3):204–220. doi: 10.1111/apha.12899

Figure 3. Pre-treatment with anti-TLR4 antibody preserved afferent arteriole autoregulatory behaviour during acute LPS treatment.

Figure 3

Pre-treatment with anti-TLR4 antibody preserves afferent arteriole autoregulatory behaviour in kidneys from LPS treated rats. (a): Effect of renal perfusion pressure changes on afferent arteriole in kidneys from control (black diamonds), LPS (1 mg kg−1; grey squares), LPS + anti-TLR4 antibody (1 μg; blue triangles), and LPS + anti-IgG2a antibody (red circles). (b): Data are expressed as a percent of the baseline diameter at 100 mmHg. Each data point represents the mean ± SE. n=6 per group. * P<0.05 vs. baseline diameter in the same group. Ϯ P<0.05 vs. control group for the same perfusion pressure. # P<0.05 vs. anti-TLR4 antibody for the same perfusion pressure.