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. Author manuscript; available in PMC: 2018 Oct 1.
Published in final edited form as: J Biomed Inform. 2017 Aug 9;74:1–9. doi: 10.1016/j.jbi.2017.08.005

Table 1.

Study design of Shigella experiments.

Study Sample size Exposure 1 Immune analysis Exposure 2 Immune analysis Exposure 3 Immune analysis
A 29 2 × 109 CFU EcSf2a-2 Post vaccination 1 × 103 CFU 2457T Post challenge
B 11 7 × 108 CFU EcSf2a-2 Post vaccination 1 × 103 CFU 2457T Post challenge
B 8 Placebo 1 × 103 CFU 2457T Post challenge
B+C 5 7 × 108 CFU EcSf2a-2 Post vaccination 1 × 103 CFU 2457T Post challenge 1.4 × 103 CFU 2457T Post challenge
B+C 6 Placebo 1 × 103 CFU 2457T Post challenge and post “vaccination” 1.4 × 103 CFU 2457T Post challenge
C 12 1.4 × 103 CFU 2457T Post challenge
C 7 1.4 × 102 CFU 2457T Post challenge