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. 2017 Oct 10;11:186. doi: 10.3389/fnbeh.2017.00186

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Copyright © 2017 Alcaraz-Iborra, Navarrete, Rodríguez-Ortega, de la Fuente, Manzanares and Cubero.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Individual consumption of 20% (v/v) ethanol (EtOH) (A), food intake (B) and body weight (BW) (C) during a single 2 h episode of drinking in the dark (DID), from which high drinkers (HD) and low drinkers (LD) subpopulations were identified [Cohort 1]. OX1r (D,E) and OX2r (F,G) mRNA expression within the NAcc and the prefrontal cortex (PFC) in HD vs. LD subpopulations. Brains were extracted after 10 days without EtOH after the DID test. All values are means ± SEM. *p < 0.05 and ***p < 0.001.