Table 1.

Pros and cons of studying biofilm in regard to bacterial diseases in Vitro vs. in Vivo.

	Pros	Cons
In vitro	Simple	No host influence
	Reproducible	Inferior in treatment studies
	Cheap	“Mushroom” structure
	Non-invasive
In vivo	Host influence	Expensive
	Ideal in treatment studies	Complex
	Natural biofilm formation	Biological variation
		Invasive