Table 5.

Synergism of alleles of G-1575A MMP-2 and C-1562T MMP-9 gene polymorphisms in fertile and infertile men

MMP-9 -1562/MMP-2-1575	Infertile men	Fertile men	OR (95% CI)	P value
Both negative MMP9 T allele and MMP-2 A allelea (CC+GG)	81 (40.5%)	57 (28.5%)	1.00
Negative MMP9 T allele and positive MMP-2 A allele (CC+AA+GA)	51 (25.5%)	61 (30.5%)	1.7 (1-2.8)	0.038 (χ2=4.29, df=1)
Positive MMP9 T allele and negative MMP-2 A allele (TT+CT+GG)	44 (22%)	50 (25%)	1.29 (1-1.7)	0.071 (χ2=3.18, df=1)
Both positive MMP9 T allele and MMP-2 A allele (TT+CT+AA+GA)	24 (12%)	32 (16%)	1.9 (1-3.5)	0.045 (χ2=4, df=1)

^a; Reference group, OR; Odds ratios, CI; Confidence interval, x²; Chi-square, and df; Degree of freedom.