Table 2.

Rate of major congenital malformations (MCM) compared in singleton assisted reproductive technology (ART) and singleton normal conception (NC) infants

Variable		MCM		OR (95% CI)(Crude)	P value(Crude)	OR (95% CI)(Adjusted)*	P value(Adjusted)
		No	Yes
Reproductive technology					0.059		0.047
	Normal	623 (95.6%)	29 (4.4%)	Reference		Reference
	ART	154 (91.7%)	14 (8.3%)	1.89 (0.98-3.66)		1.89 (1.01-3.66)
Sex					0.87		0.79
	Boy	397 (95%)	21 (5%)	Reference		Reference
	Girl	380 (94.5%)	22 (5.5%)	1.09 (0.59-2.02)		1.08 (0.58-2.01)
Maternal age (Years)					0.56		0.73
	<35	622 (95 %)	33 (5%)	Reference		Reference
	>35	155 (93.9%)	10 (6.1%)	1.22 (0.59-2.52)		1.14 (0.54-2.37)
History of stillbirth					0.48		0.74
	No	766 (94.8%)	42 (5.2%)	Reference		Reference
	>1	11 (91.7%)	1 (8.3%)	1.96 (0.21-13.15)		1.41 (0.17-11.38)
History of abortion					0.129		0.65
	No	540 (95.6%)	25 (4.4%)	Reference		Reference
	>1	237 (92.9%)	18 (7.1%)	1.64 (0.88-3.06)		1.21 (0.53-2.76)
Delivery					0.25		0.34
	Normal	107 (97.3%)	3 (2.7%)	Reference		Reference
	Cesarean	670 (94.4%)	40 (5.6%)	2.13 (0.65-7.01)		1.80 (0.53-6.04)

*; Adjusted for all variables in Table 1. OR; Odds ratio and CI; Confidence interval.