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. 2017 Aug 18;28(6):e77. doi: 10.3802/jgo.2017.28.e77

Table 3. Multivariate Cox regression analysis with PFS and OS as endpoint.

Factors PFS OS
HR 95% CI p-value HR 95% CI p-value
Pretreatment serum CA125 level (<244 U/mL vs. ≥244 U/mL) 0.922 0.457–1.860 0.820 0.578 0.259–1.292 0.182
Ascitic fluid (positive vs. negative) 1.110 0.883–3.566 0.107 1.111 0.511–2.414 0.790
FIGO stage (advanced vs. early) 10.165 4.513–22.894 <0.001 14.323 4.744–43.240 <0.001
PD-L1 expression (high vs. low) 1.970 1.039–3.737 0.038 3.032 1.285–7.153 0.011
Tumor volume (<10 cm vs. ≥10 cm) 0.928 0.069–1.248 0.621 0.752 0.513–1.102 0.144
Residual disease (>1 cm vs. R0, ≤1 cm) 1.063 0.566–1.999 0.849 1.767 0.824–3.787 0.143

CI, confidence interval; FIGO, International Federation of Gynecology and Obstetrics; HR, hazard ratio; OS, overall survival; PD-L1, programmed death-ligand 1; PFS, progression-free survival; R0, no visible residual disease.