Table 3.

Mean relative abundances (RA) at the different levels.

Phylum	Class	Order	Family	Genus	Before PPI	On PPI	After PPI
Firmicutes					0.544	0.565	0.551
	Clostridia	Clostridiales	Ruminococcaceae		0.040	0.044	0.095*#
				Oscillospira	3.1 × 10−3	1.7 × 10−3	6.4 × 10−3*#
				Faecalibacterium	3.3 × 10−3	3.7 × 10−3	9.2 × 10−3
				Ruminococcus	2.9 × 10−3	2.1 × 10−3	5.1 × 10−3*#
			Veillonellaceae		0.128	0.107	0.056*#
				Veilonella	0.119	0.096	0.026*#
				Phascolarctobacterium	0	3.7 × 10−7	9.3 × 10−3*
			Lachnospiraceae		0.115	0.158	0.249*
				Lachnospira	4.3 × 10−3	0.016	0.018*#
				Blautia	0.015	0.017	0.036*#
				Coprococcus	6.8 × 10−3	7.5 × 10−3	0.022*#
				Dorea	4.8 × 10−4	1.3 × 10−4	1.3 × 10−3*#
				Anaerostiges	7.2 × 10−5	0	0
	Bacilli	Lactobacillales	Lactobacillaceae	Lactobacillus	2.6 × 10−4	2.9 × 10−5*	3.4 × 10−5*
	Erysipelotrichi	Erysipelotrichales	Erysipelotrichaceae	Eubacterium	2.6 × 10−3	5.5 × 10−4	3.7 × 10−3*#
				Coprobacillus	3.2 × 10−5	1.2 × 10−4	1.8 × 10−3*#
Bacteroidetes					0.302	0.272	0.376
	Bacteroidea	Bacteroidales	Rikenellaceae	Bacteroides	6.3 × 10−5	4.8 × 10−5	0.010#
Proteobacteria					0.11	0.13	0.03*
	Gammaproteobacteria				0.087	0.117	0.017*#
		Enterobacteriales	Enterobacteriaceae	Escherichia	0.086	0.110	0.017*#
		Xanthomonadales	Xanthomonadaceae	Stenotrophomonas	5.1 × 10−5	1.6 × 10−6*	1.6 × 10−6*#
		Pasteurellales	Pasteurellaceae	Haemophilus	0	2.3 × 10−5*	1.8 × 10−6
Acinetobacteria					0.024	0.020	0.023
	Coriobacteria	Coriobacteriales	Coriobacteriaceae	Adlercreutzia	0	0	3.7 × 10−5
Cyanobacteria					2.2 × 10−5	3.1 × 10−6	3.8 × 10−3
Verrucomicrobia					1.7 × 10−3	0	4.9 × 10−4
Fusobacteria					5.4 × 10−4	1.5 × 10−3	4.1 × 10−4
TM7					2.3 × 10−5	4.5 × 10−5	7.0 × 10−5

^*p < 0.05 vs. “before PPI”;

^#p < 0.05 vs.

“on PPI.” Significant increases under PPI therapy are colored in blue, significant decreases in red.