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. 2017 Oct 11;4:155. doi: 10.3389/fmed.2017.00155

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Copyright © 2017 Roux, Bendib Le Lan, Holifanjaniaina, Thomas, Picard, Grenet, De Miranda, Douvry, Beaumont-Azuar, Sage, Devaquet, Cuquemelle, Le Guen, Suberbielle, Gautreau, Stern, Rossetti, Hamid and Parquin.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Sum mean fluorescence intensity (MFI) of donor specific antibody (DSA) at peak according to antibody-mediated rejection (AMR) status. Peak was defined as the time point of DSA with the highest sum MFI for AMR^Neg (DSA^PosAMR^Neg) patients, or as the time of AMR diagnosis for AMR^Pos patients. (A) The sum MFI of each patient’s DSA is indicated by each circle. The table below lists the number of patients, median and mean sum MFI, and number of specificities for each patient group. (B) ROC curve for use of sum MFI as a predictor of AMR diagnosis and the specificity/sensitivity according to MFI different cutoffs. Significance values are denoted above lines over compared groups.