Figure 2.

Immunofluorescence detection of GLUT2 and SGLT2 levels in 24-wk ArcPomc^−/− mice. A) Reduced GLUT2 levels in proximal tubular cells, but no change in its distribution or location, in ArcPomc^−/− mice; B) No change in proximal tubular SGLT2 levels in ArcPomc^−/− mice. *P < 0.05, 2-tailed Student's t-test was used for comparisons; n = 6. Error bars reflect mean ± SEM. Scale bar = 33 μm; images were taken under 40× objective lens field.