Table 2.
Regulation of mRNA expression of MKPs in human skeletal muscle at baseline after acute exercise
| MKPs | 0 h versus pre‐exercise | 2 h versus pre‐exercise | ||||
|---|---|---|---|---|---|---|
| All | Control | Dysglycemic | All | Control | Dysglycemic | |
| DUSP5 | 10.85 ± 1.28 | 11.18 ± 1.72 | 10.45 ± 2.00 | 1.25 ± 0.14 | 1.34 ± 0.25 | 1.16 ± 0.13 |
| DUSP2 | 6.77 ± 1.48 | 7.45 ± 2.29 | 5.96 ± 1.87 | 8.31 ± 0.94 | 9.36 ± 1.58 | 7.16 ± 0.90 |
| DUSP1 | 4.00 ± 0.55 | 4.45 ± 0.79 | 3.47 ± 0.76 | 0.41 ± 0.07 | 0.39 ± 0.07 | 0.44 ± 0.09 |
| DUSP8 | 2.19 ± 0.19 | 2.42 ± 0.31 | 1.91 ± 0.15 | 1.23 ± 0.11 | 1.26 ± 0.19 | 1.19 ± 0.11 |
| DUSP4 | 1.97 ± 0.30 | 2.16 ± 0.42 | 1.74 ± 0.45 | 2.36 ± 0.34 | 2.73 ± 0.55 | 1.96 ± 0.38 |
| DUSP16 | 1.51 ± 0.05 | 1.52 ± 0.07 | 1.50 ± 0.08 | 1.15 ± 0.04 | 1.22 ± 0.05 | 1.09 ± 0.07 |
| DUSP10 | 1.23 ± 0.07 | 1.20 ± 0.07 | 1.26 ± 0.13 | 0.56 ± 0.05 | 0.59 ± 0.09 | 0.51 ± 0.05 |
| DUSP7 | 0.99 ± 0.04 | 1.00 ± 0.06 | 0.97 ± 0.04 | 0.72 ± 0.04 | 0.74 ± 0.07 | 0.71 ± 0.05 |
| DUSP6 | 0.62 ± 0.06 | 0.61 ± 0.07 | 0.63 ± 0.09 | 0.72 ± 0.06 | 0.72 ± 0.09 | 0.73 ± 0.07 |
Data represent mean fold changes ± SEM for all participants together (n = 24) or for separate groups (n = 11, controls; n = 13, dysglycemics); P‐values were calculated by paired Student's t‐test, P < 0.05 versus pre‐exercise (bold). Baseline pre‐exercise values are presented in Table 1. MKPs, MAPK phosphatases; DUSP, dual specificity phosphatase.