Table 2. In Vitro Mammalian Cytotoxic Activity of BPEIa.
mean
IC50 ± SD (μM) |
||||
---|---|---|---|---|
human cell line | 600 Da | 1200 Da | 1800 Da | 10 kDa |
cervical cancer (HeLa) | 1820 ± 250 | 692 ± 13 | 519 ± 34 | 0.66 ± 0.089 |
colon cancer (HCT116) | 487 ± 75 | 457 ± 48 | 100 ± 42 | 1.11 ± 0.22 |
kidney cancer (HEK293) | 1150 ± 130 | 155 ± 23 | 33 ± 13 | 0.19 ± 0.05 |
Values are reported as the average of three trials ± standard deviation. Cells were treated for 48 h and assayed with the CellTiter Blue method.