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. 2017 Sep 18;8(10):1007–1012. doi: 10.1021/acsmedchemlett.7b00192

Table 1. Activities of Apratoxin S10 and Known RTKs Inhibitors on a Range of Cancer Cells, IC50 (nM)a.

  renal hepatocellular neuroendocrine
  A498 Huh7 NCI-H727
apratoxin S10 (1) 3.35 ± 0.34 0.83 ± 0.06 2.55 ± 0.19
sunitinib 7981 ± 1194 4707 ± 492 10120 ± 1179
erlotinib ∼12500 ∼25000 >6240
cabozantinib 8456 ± 2046 4348 ± 708 14010 ± 2813
a

Determined after 48 h (n = 3).