Skip to main content
. 2015 Aug 13;26(5):2287–2318. doi: 10.1177/0962280215597260

Table A 2.1.

Predictions obtained from BRMA PTDF models (and BRMA PNF for comparison) for all studies in the ‘Sormani data’.

Disability progression rate ratio, mean (95% CrI)
Paty (1) Paty (2) Miligan Johnson Jacobs/Simon
Observed 1.00 (0.67, 1.49) 0.71 (0.45, 1.12) 1.14 (0.26, 5.03) 0.88 (0.57, 1.35) 0.63 (0.38, 1.05)
BRMA PNF 0.98 (0.63, 1.53) 0.83 (0.51, 1.36) 0.86 (0.19, 3.96) 0.86 (0.54, 1.39) 0.85 (0.49, 1.47)
BRMA PTDF (4 df) 0.98 (0.62, 1.55) 0.83 (0.51, 1.37) 0.86 (0.19, 3.97) 0.86 (0.53, 1.39) 0.85 (0.49, 1.47)
BRMA PTDF (15 df) 0.98 (0.63, 1.53) 0.84 (0.51, 1.36) 0.88 (0.19, 4.05) 0.86 (0.53, 1.39) 0.85 (0.49, 1.46)
BRMA PTDF (30 df) 0.98 (0.63, 1.53) 0.84 (0.51, 1.36) 0.87 (0.19, 4.01) 0.86 (0.53, 1.39) 0.84 (0.49, 1.46)
Fazekas Millefiorini Achiron Li (1) Li (2)

Observed 0.70 (0.36, 1.35) 0.19 (0.05, 0.79) 0.82 (0.19, 3.50) 0.81 (0.61, 1.08) 0.73 (0.54, 0.99)
BRMA PNF 0.66 (0.33, 1.33) 0.64 (0.15, 2.75) 0.65 (0.15, 2.86) 0.87 (0.62, 1.23) 0.85 (0.60, 1.21)
BRMA PTDF (4 df) 0.66 (0.32, 1.35) 0.64 (0.15, 2.77) 0.66 (0.15, 2.94) 0.87 (0.61, 1.23) 0.86 (0.60, 1.23)
BRMA PTDF (15 df) 0.66 (0.33, 1.33) 0.64 (0.15, 2.74) 0.66 (0.16, 2.89) 0.87 (0.62, 1.23) 0.85 (0.60, 1.21)
BRMA PTDF (30 df) 0.66 (0.33, 1.34) 0.64 (0.15, 2.75) 0.66 (0.15, 2.88) 0.87 (0.61, 1.22) 0.85 (0.60, 1.21)
Clanet Durelli Baumhackl Polman Rudick

Observed 1.00 (0.83, 1.20) 0.43 (0.24, 0.78) 1.07 (0.74, 1.57) 0.59 (0.46, 0.75) 0.79 (0.65, 0.96)
BRMA PNF 1.09 (0.82, 1.45) 0.87 (0.47, 1.63)* 0.94 (0.61, 1.43) 0.57 (0.40, 0.82) 0.66 (0.50, 0.87)
BRMA PTDF (4 df) 1.08 (0.81, 1.45) 0.87 (0.46, 1.62)* 0.93 (0.60, 1.45) 0.57 (0.39, 0.83) 0.66 (0.50, 0.88)
BRMA PTDF (15 df) 1.08 (0.81, 1.44) 0.87 (0.46, 1.62)* 0.93 (0.61, 1.43) 0.57 (0.39, 0.82) 0.66 (0.50, 0.87)
BRMA PTDF (30 df) 1.08 (0.82, 1.43) 0.87 (0.46, 1.62)* 0.94 (0.61, 1.44) 0.57 (0.39, 0.82) 0.66 (0.50, 0.87)
Coles (1) Coles (2) Mikol Comi (1) Comi (2)

Observed 0.35 (0.16, 0.74) 0.38 (0.19, 0.77) 1.34 (0.88, 2.06) 0.69 (0.52, 0.93) 0.73 (0.55, 0.97)
BRMA PNF 0.61 (0.27, 1.35) 0.53 (0.25, 1.12) 1.01 (0.62, 1.64) 0.66 (0.45, 0.96) 0.68 (0.47, 0.98)
BRMA PTDF (4 df) 0.60 (0.27, 1.36) 0.52 (0.24, 1.14) 1.01 (0.61, 1.64) 0.66 (0.45, 0.97) 0.68 (0.47, 0.99)
BRMA PTDF (15 df) 0.61 (0.27, 1.35) 0.53 (0.25, 1.14) 1.00 (0.62, 1.62) 0.66 (0.45, 0.96) 0.68 (0.47, 0.98)
BRMA PTDF (30 df) 0.60 (0.27, 1.35) 0.53 (0.25, 1.13) 1.01 (0.62, 1.63) 0.66 (0.45, 0.96) 0.68 (0.48, 0.98)
Havrdova (1) Havrdova (2) Sorensen O'Connor (1) O'Connor (2)

Observed 1.23 (0.58, 2.62) 1.04 (0.48, 2.67) 0.64 (0.32, 1.28) 1.05 (0.84, 1.31) 1.10 (0.88, 1.37)
BRMA PNF 0.95 (0.43, 2.08) 0.85 (0.38, 1.90) 0.65 (0.31, 1.37) 1.06 (0.77, 1.45) 1.00 (0.74, 1.35)
BRMA PTDF (4 df) 0.94 (0.43, 2.06) 0.85 (0.38, 1.90) 0.66 (0.31, 1.40) 1.06 (0.76, 1.49) 0.99 (0.73, 1.35)
BRMA PTDF (15 df) 0.95 (0.43, 2.08) 0.85 (0.38, 1.90) 0.65 (0.31, 1.43) 1.06 (0.77, 1.46) 1.00 (0.73, 1.35)
BRMA PTDF (30 df) 0.94 (0.43, 2.06) 0.85 (0.38, 1.90) 0.65 (0.31, 1.44) 1.06 (0.77, 1.45) 0.99 (0.74, 1.34)