Table 1.
Case No. | Age sex | Antibody status A = AChRA, M = MUSK |
Thymus | Thym- ectomy |
MG therapy before SCIG | Concurrent MG therapy | No. of PLEX/year prior to starting SCIG | No. of PLEX/year after starting SCIG | MGFA score before SCIG | MGFA score after SCIG | MG-QOL-R score before SCIG | MG-QOL-R score after SCIG |
---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | 45 F | A + | Hyperplasia | Yes | Mpred 8–24 mg/d, AZT 150 mg/d, Pyrido 300 mg/d | Mpred 2 mg/d, Pyrido 300 mg/d | 5 | 0 | 19 | 9 | 27 | 18 |
2 | 47 F | A -, M - | No | No | Mpred 16–48 mg/d, Cy: 500 mg/month, Pyrido: 300 mg/d | Mpred 16 mg/d, MTX 15 mg/w, Pyrido: 300 mg/d | 5 | 0 | 18 | 12 | 26 | 20 |
AChRA, acetylcholine receptor antibody; AZT, azathioprine; Cy, cyclophosphamide; MG, myasthenia gravis; MGFA, Myasthenia Gravis Foundation of America; MG-QOL-R, myasthenia gravis quality of life; Mpred, methylprednisolone; MTX, methotrexate; MUSK, Muscle-specific kinase antibody; No., number; PLEX, plasma exchange; Pyrido, pyridostigmine; SCIG, subcutaneous immunoglobulin.