Table 1. Biological Profiling of Computationally Evolved Analogues of CD117.

^aWorkflow (i), shown in Figure 2.

^bWorkflow (ii), shown in Figure 2.

^cWorkflow (iii), shown in Figure 2.

^dMLM stability from assay as represented by t_1/2 (min).

^eMLM Cl_int as represented by μL/min/mg protein.

^fMIC against Mtb H37Rv in μg/mL.

^gVero Cell toxicity as represented by CC₅₀ in μg/mL.