Table 1. Cell-Based Readthrough Activity of Derivatives 10a–f.
Yields were calculated from intermediate 8 for analogues 3 and 10a–f, respectively.
Cell-based readthrough activity (ratio) relative to control (D-MEM) in COS-7 cells; compounds are evaluated at a concentration of 200 μM. Values are expressed as the mean ± SD (n = 3).
See ref (21).
N.a: not applicable.