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. 2017 Sep 8;8(10):1077–1082. doi: 10.1021/acsmedchemlett.7b00283

Table 5. PK Profile of 1o and 1q in Mouse Cassettea.

  AUCpo (ng h/mL)b F (%)c
1a 9.0 5.7
1o 146.6 16.1
1q 315.4 23.7
a

Male ICR mice (n = 3). Dose: i.v. at 0.1 mg/kg; p.o. at 1 mg/kg.

b

Area under the curve from 0 to 8 h.

c

Bioavailability.