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. 2017 Oct 5;61(1):1379861. doi: 10.1080/16546628.2017.1379861

Figure 2.

Figure 2.

Treatment with PTE inhibited lipid accumulation in HFD-induced obese mice without altering food intake. Obese mice derived from HFD feeding for 4 weeks were divided into the HFD control group (n = 10) and PTE treatment group (n = 10). Mice in the HFD control group received distilled water, whereas mice in the PTE group were administered 250 mg/kg PTE orally daily for 5 weeks. The normal diet group (ND, n = 8) were fed a ND throughout the entire experiment period. (a) Phenotypes of mice in ND, HFD control, and PTE treatment groups. Scale bar = 4 cm. (b) Body weight (g) plot of each experimental group during the treatment period. (c) Average increased body weight (g) of each experimental group. (d) Body weight (%) plot at each measurement day relative to the first day of treatment during the experimental period. (e) Mean relative increased body weight (%) of each group after treatment for 5 weeks. (f) Weight of epididymal fat of mice in each experimental group after treatment for 5 weeks. (g) Amounts of food intake in the HFD control and PTE treatment groups. Data are presented as mean ± SEM. Significant differences between the ND group and HFD control group are indicated by #p < 0.05, ##p < 0.01, and ###p < 0.001. Significant differences between the PTE group and HFD control group are indicated by *p < 0.05, **p < 0.01, and ***p < 0.001.