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. Author manuscript; available in PMC: 2018 Jul 6.
Published in final edited form as: Cell Stem Cell. 2017 Jul 6;21(1):78–90.e6. doi: 10.1016/j.stem.2017.06.014

Figure 4. Single-cell transcriptomics of Prox1-GFP+ cells.

Figure 4

A. t-SNE projection of 1,051 Prox1-GFP+ cells colored by clustering. B. Expression of key genes including Prox1 and markers of stem/progenitor cells. Lgr5, Ascl2 and Olfm4 represent canonical CBC markers whereas Nfat5, Nfatc3 and Cd83 are LRC/secretory progenitor makers. C. Tuft cell marker expression among the Prox1-GFP+ clusters. D. EE marker expression among the Prox1-GFP+ clusters. E. Immunofluorescence validation of EE (ChgA) and tuft (Dclk1) marker expression in Prox1+ cells. Bar = 20 µm.