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0.5 mg/kg Diazepam did not potentiate the antinociception produced by oxycodone in the tail immersion test. (n = 10–20). Latency to tail withdrawal (% MPE ± SEM) among mice that were drug naïve or pretreated with diazepam 30 minutes before testing. Various doses of the oxycodone were used for construction of dose-response curves for calculation of ED50 values.
