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. 2017 Oct 16;136(16):1495–1508. doi: 10.1161/CIRCULATIONAHA.117.028084

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© 2017 The Authors.

Circulation is published on behalf of the American Heart Association, Inc., by Wolters Kluwer Health, Inc. This is an open access article under the terms of the Creative Commons Attribution License, which permits use, distribution, and reproduction in any medium, provided that the original work is properly cited.

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Figure 2. — Baseline distribution of cMyC levels at presentation to the emergency department in all patients based on adjudicated final diagnosis. Boxes represent interquartile ranges (IQR). Whiskers extend to 1.5*IQR from the hinges (y axis capped at 1500 ng/L, outliers represented by light gray bullets); 87 ng/L represents the 99th percentile based on a previous study and 120 ng/L the cutoff threshold for diagnostic rule-in of AMI at presentation. AMI, median, 237 ng/L (IQR 71, 876 ng/L); unstable angina, median, 21 ng/L (IQR 13, 43 ng/L); cardiac symptoms of origin other than coronary artery disease, median, 33 ng/L (IQR 12, 96 ng/L); noncardiac symptoms, median, 10 ng/L (IQR 6, 19 ng/L; symptoms of unknown origin, median, 11 ng/L (IQR 7, 16 ng/L) (P<0.001 for all comparisons with patients with AMI). AMI indicates acute myocardial infarction; cMyC, cardiac myosin-binding protein C; and UA, unstable angina.