Figure 7.

Role of MAPKs in TF2a and TF2b-induced apoptosis and G1 cell cycle arrest in A2780/CP70 cells. (A) Protein expression levels of p38, p-p38, ERK1/2, p-ERK1/2, JNK1/2 and p-JNK1/2 were analyzed by western blotting. A2780/CP70 cells were treated with designated concentrations (0, 5, 10 and 20 µM) of TF2a and TF2b for 24 h. The changes of the protein expression induced by TF2a (B) and TF2b (C) were expressed as quantification histograms with error bars. Results are expressed as mean ± SD from three independent experiments. Significant differences among different treatments are marked with different letters (p<0.05).