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. 2017 Sep 14;51(5):1405–1414. doi: 10.3892/ijo.2017.4123

Figure 4.

Figure 4

hAECs regulate the expression of proteins related to G0/G1 cell cycle arrest determined by IHC. hAECs upregulated p16INK4A, p21 and phospho-JNK expression and downregulated phospho-pRB (Ser807) expression in EOC cells (n=5). Scale bar of (A), (B) and (C) were 100 µm and that of (D) was 50 µm. H-score system was used for semi-quantification of p16INK4A, p21 and phospho-JNK between two groups. Data were analyzed by Mann-Whitney U test and presented as means ± SEM. **p<0.01.