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. 2017 Sep 1;8(41):69362–69369. doi: 10.18632/oncotarget.20618

Table 2. Odds ratios (OR) and 95% confidence intervals (CI) for carotid atherosclerosis.

Handgrip strength tertiles 1 SD increment in handgrips strength
T1 (low) T2 T3 (high) p for trend
Total subjects
 No. at risk 272 266 257
 No. of cases (percentage) 44 (16.2) 45 (16.9) 37 (14.4)
 Sex-and age-adjusted OR 1.00 1.32 (0.82, 2.11) 1.52 (0.89, 2.63) 0.117 1.20 (0.96, 1.50)
 Multivariable OR 1.00 1.32 (0.81, 2.16) 1.58 (0.89, 2.80) 0.111 1.23 (0.97, 1.56)
Lower platelets count
 No. at risk 123 142 129
 No. of cases (percentage) 29 (23.6) 20 (14.1) 15 (11.6)
 Sex-and age-adjusted OR 1.00 0.63 (0.33, 1.20) 0.65 (0.30, 1.38) 0.208 0.78 (0.56, 1.08)
 Multivariable OR 1.00 0.75 (0.38, 1.50) 0.78 (0.35, 1.74) 0.505 0.86 (0.61, 1.22)
Higher platelets count
 No. at risk 149 124 128
 No. of cases (percentage) 15 (10.1) 25 (20.2) 22 (17.2)
 Sex-and age-adjusted OR 1.00 3.10 (1.50, 6.41) 4.00 (1.76, 9.10) <0.001 1.80 (1.29, 2.51)
 Multivariable OR 1.00 2.82 (1.30, 6.11) 3.75 (1.54, 9.17) 0.004 1.82 (1.26, 2.64)

Multivariable OR: adjusted further for age and sex, systolic blood pressure, body mass index, smoking status, alcohol intake, serum triglycerides, serum HDL-cholesterol, and HbA1c. Handgrip strength levels tertiles: <25.5 kg, 25.5-35.0 kg, and >35.0kg for men and <18.5kg, 18.5-22.0kg, and >22.0kg for women. Lower platelets are defined as < 21.6×104 /μL for men and < 22.6×104 /μL for women. Carotid atherosclerosis is defined as a carotid intima-media thickness ≥1.1mm. SD: standard deviation. 1 SD increment in handgrips strength are 9.4kg for men and 5.0kg for women.