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. 2017 May 13;8(41):69508–69519. doi: 10.18632/oncotarget.17843

Figure 5. Oxadiazole derivatives suppress AR-related function in vivo.

Figure 5

(A) The mice with LNCaP cell xenograft after 28 days of treatment with DMSO, CDX, LHJ-647, and HWC-489. (B) Tumor volumes measured during treatment in NOD/SCID mice. HWC-489, LHJ-647, and CDX exerted significant effects, compared to vehicle treatment. (C) Tumor weights measured after sacrificing mice on day 28 of treatment. (D) Mouse body weights of all four groups displayed no significant changes during the treatment period.