Table 1. FxxFY motif was rich in bicalutamide (CDX)-W741L-AR associated peptide and most of screened peptides can interact with DHT-wt-AR and also with CDX-W741L-AR in MM2H assay.

Peptide				wt-AR		W741L-AR
	−1	+ 1 + 4 + 5	+6	Ethanol	DHT	Ethanol	CDX
Gal-4				1	1	1	1
1.C411-FY	NDTPVK	FAHFY	H	7	3	2	3
2.C414-FY	NPSSM	FEKFY	LR	10	2,653	2	532
3.C1-FY	SYT	FNQFY	YSTA	19	680	8	511
4.C412-FY	APSDTY	FQRFY	R	12	6	1	2
5.CA-10-FY	EHSM	FHSFY	VQG	12	277	4	14
6.C8-FY	GD	FKSFY	LATTW	17	484	2	86
7.C315-FY	APSLNR	FATFY	H	1	6	1	2
8.CA9-FY	SL	FTSFY	TGSGS	20	1,517	5	190
9.C4-FY	SPL	FSSFY	HART	4	340	1	114
10.CA23-FY	IQPSL	FAQFY	HP	46	213	32	4,118
11.CON-1	MYKP	HNHHQ	TSS	1	1	1	1
12.#3-18	NTNA	FSRLF	YPS	10	590	9	128
13.RIP-p	GIEEK	FRPFY	LSQLE	2	159	12	554

*Con-1, negative control.

**^#3–18, positive control.

***RIP-p, short peptide of novel AR coregulator candidate.

DHT = 10 nM, CDX = 10 µM.