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. 2017 Jul 18;8(41):69847–69862. doi: 10.18632/oncotarget.19349

Table 1. Functional annotation of both KEAP1 overexpression and NRF2-KD down regulated genes in A549 cells.

Term Count p-value
GO_Biological Proceess (GO_BP)
GO:0055114∼oxidation-reduction process 17 4.39E-04
GO:0044281∼small molecule metabolic process 34 5.73E-04
GO:0008285∼negative regulation of cell proliferation 13 0.001240062
GO:0034113∼heterotypic cell-cell adhesion 4 0.001398769
GO:0006919∼activation of cysteine-type endopeptidase activity involved in apoptotic process 6 0.001591679
KEGG Pathway
hsa00350:Tyrosine metabolism 4 0.011399894
hsa00360:Phenylalanine metabolism 3 0.021483079
hsa00982:Drug metabolism - cytochrome P450 4 0.028043883
hsa00340:Histidine metabolism 3 0.037935313
hsa01100:Metabolic pathways 24 0.052438531