Table 1. Properties of the main vectors used in gene therapy protocols.
Vector | Integrative | in vitro delivery efficiency | in vivo delivery Efficiency | Capacity to trigger immune response | Efficient production |
---|---|---|---|---|---|
Adenoviral | No | High | High | High | Yes |
Lentiviral | Yes | High | High | Low | No |
Retroviral | Yes | High | High | Low | No |
AAV | No | High | High | High | No |
Liposomes | No | High | Low | Low | Yes |
Abbreviations: AAV, Adeno-associated virus.