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Cell motility was inhibited by si-NIPBL in scratch assays and invasion assays of breast cancer cells in vitro. The scratch assay shows delayed wound healing. (A, B) Wound distance percentage of MCF-7 for 0 and 72 h after si-NIPBL treatment. (C, D) Invasion assay of MCF7 and Bcap37 cells after 24 h of transfection with si-NIPBL; (* P<0.05: ** P<0.01; *** P<0.001). Data are presented as mean ±SD of experiments performed in triplicate.
