Fig. S3.

Gene dosage requirement of Yap and Taz during retinal angiogenesis. (A) Whole-mount IB4 staining of P5 control, Yap^flox/flox; Pdgfb-iCreERT2 (Yap cKO), Taz^flox/flox; Pdgfb-iCreERT2 (Taz cKO), Yap^flox/flox; Taz^wt/flox; Pdgfb-iCreERT2 (Yap cKO; Taz cHet), and Yap/Taz cKO retina. (B–E) Quantification of the vascular extension (n = 6), vascular area (n = 3), number of branchpoints (n = 6), and tip cells (n = 4); mean ± SD, *P < 0.01 (Tukey–Kramer test). [Scale bars: 500 μm (Left) and 200 μm (Right).]